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Tramadol a possible treatment for PE

Updated Dec 6, 2007 at 8:30 EST.


The American Urological Association had its annual meeting recently to discuss the current knowledge and continuing research in the field of sexual medicine.   Wayne J. G. Hellstrom MD covered the event in his recent article, "Sexual Dysfunction: Highlights from AUA 2007”.

 

Tramadol was mentioned in the meeting as a possible effective treatment for premature ejaculation.  Tramadol is an analgesic (pain killer).   This medicine combines both opioid receptor activation and reuptake inhibition of 5-hydroxytryptamine ( 5-HT ) and non adrenaline.   Some testing of the drug was also brought up at the meeting.  A single blind placebo study was administered on 60 men suffering from premature ejaculation.   In the study, Tremadol was given to patients 1-2 hours before intercourse and compared with the placebo group.   The results were calculated by a stopwatch.   The results showed ejaculation latency times increasing 6 times from 21 seconds to 243 seconds in the Tramadol group.   The intercourse rate doubled and the satisfaction levels calculated by IIEF also improved.   Neither the placebo group nor the Tremenol group underwent withdrawals.   This testing is just the beginning for this new drug, much more research and studies are needed before it is ready to be approved for the treatment of PE.



Written by the PEhomepage.com Editorial Team.



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